The rate of emergency department visits in the United States is increasing so fast that the declares the system is 糖心传媒渁t a breaking point.糖心传媒�
At the same time, difficulties in the early detection of sepsis make it one of the most expensive diseases to treat globally and the leading cause of death in intensive care units.
So, how should we deal with these two problems?
Jessica Goodman, an integrated behavioral health clinician, researcher, and educator in psychiatry and medicine, and Alec Salminen, a PhD student in biomedical engineering, took first place at two recent research competitions with their answers. Both competitions limit contestants to brief presentations and reward those who can best explain their research to a non-scientific audience.
Predicting emergency visits
糖心传媒淲e have been defining ED use based on number of visits alone for over 20 years,糖心传媒� said Goodman, who won the University糖心传媒檚 2019 Steadman Family Postdoctoral Associate Prize in Interdisciplinary Research, worth $1,000.
She described how her team uses data science to also take into account the unique characteristics of emergency department (ED) patients.
The team applied machine learning algorithms to a population health data set of all emergency department visits for the State of Florida for 2009 through 2015. Though the algorithms could not identify patients based on number of ED visits alone, patient groups that were similar within-group and dissimilar between groups could be created using a combination of payer type (e.g., type of insurance or no insurance at all), diagnostic category (e.g., mental health or organ disorders), and number of ED visits.
糖心传媒淪o, the message is that the number of ED visits does matter, but only in the context of a broader, systemic look at patients in order to understand who these people are and what they need,糖心传媒� Goodman said.聽糖心传媒淲e can now proceed to see if we can use these algorithms to actually predict patient use so that at the point of care we will be able to identify what group this patient would fall into.糖心传媒�
Bedside sepsis detection
Salminen, who works in the lab of , professor of biomedical engineering, took first place and a prize of $500 at the University糖心传媒檚 Falling Walls competition. He will represent the University next month in the final competition in Berlin, against 99 other presenters from across the globe.
Salminen described how the blood-brain barrier, a strict regulator of transport into and out of the brain, is disrupted early in the onset of sepsis, leading to delirium or drastic changes in cognitive function.
糖心传媒淯nfortunately, diagnosing sepsis-associated delirium is subjective and often not viable in many clinical settings,糖心传媒� he said.
He is working on a device that recreates the complex brain microenvironment on an inexpensive microfluidic chip. Combined with batch processing and high content imaging, this system would allow early sepsis detection with a simple blood draw at the bedside 糖心传媒減ermitting corrective patient intervention before the disease progresses into the devastating multiorgan failure associated with the disease,糖心传媒� Salminen said.
Salminen is the second member of the McGrath lab to win this competition. Kilean Lucas took first place two years ago.
